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DTSTART;VALUE=DATE:20241217T110000
DTEND;VALUE=DATE:20241217T114500
UID:17038@agenda.unifr.ch
DESCRIPTION:Public lecture as part of the search for a Professor in Pathology\n\nAbstract: Lung and pancreatic cancers, driven by KRAS mutations, exhibit profound metabolic adaptations that promote cancer progression and resistance to therapy. Among these adaptations, lipid metabolism plays a pivotal role in shaping tumor-stroma crosstalk, ultimately driving fibrosis, immune evasion, and metastasis. By integrating advanced tumor models with high-resolution lipidomic and transcriptomic analyses, we highlight how key lipid metabolic dysregulations in these aggressive cancers can be uncovered as tumor-specific vulnerabilities and identified as relevant cancer biomarkers to inform the development of personalized therapeutic strategies.
SUMMARY:Harnessing Lipid Metabolism to Uncover Tumor Vulnerabilities for Cancer Therapy
CATEGORIES:Conférence\, Cours public
LOCATION:PER 21\, Auditorium C130\, Bd de Pérolles 90\, 1700 Fribourg
URL;VALUE=URI:https://agenda.unifr.ch/e/fr/17038
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